Backlog and slipping turnaround
Cases accumulate faster than they clear, putting reporting commitments under pressure.
Clinical Operations
Turn sequencing data into reliable clinical reporting.
Expand clinical reporting capacity and build internal expertise through Interpretation Services and workforce development.
Three pressures on the reporting queue.
As testing programs grow, laboratories can face increasing pressure on interpretation capacity, turnaround time, and expertise.
Analyst capacity you can’t hire fast enough
Variant scientists are scarce, and recruiting and training new analysts can take longer than growing reporting demand allows.
Expanding beyond current expertise
New variant classes or reporting requirements may require expertise the existing review team does not yet have.
The outcome
What success looks like.
- Deliver reports on time, even as volumes grow
- Expand reporting capacity without adding headcount
- Support new variant classes and reporting requirements with confidence
- Maintain consistent interpretation quality across reviewers
- Build and demonstrate internal interpretation expertise
Over 90%
Proven outcome
of cases finalized in less than 48 hours
How we help
Add capacity, build expertise, or both.
Need interpretation capacity?
Interpretation Services
PierianDx variant scientists interpret scoped cases within CGW, while clinical review and sign-out remain with the laboratory .
See what Interpretation Services includes ↓
Want to build internal expertise?
Variant Analyst Certification Program
Structured training, assessment, and certification help laboratories develop and demonstrate internal variant interpretation competency .
Explore the Variant Analyst Certification Program →The two approaches can also work together: Interpretation Services can add reporting capacity while internal analysts build expertise.
Interpretation Services
Scientific expertise when you need additional capacity.
Case interpretation
Somatic, germline, and scoped validation case interpretation.
Variant classification
Evidence review and classification of relevant genomic findings.
Reporting support
Interpretations returned through CGW for laboratory review and sign-out .
Scientific escalation
Additional scientific review for challenging variants or interpretation questions.
Runs on PierianDx · Clinical Genomics Workspace
Interpretation happens where your cases already live.
- Interpretation within CGW. PierianDx variant scientists review and interpret scoped cases directly within CGW.
- Review history stays with the case. Evidence, interpretation, and case activity remain connected within the workflow.
- Reporting stays connected. Interpretation output remains in CGW for laboratory review and downstream reporting.
| Gene | Variant | VAF | Tier |
|---|---|---|---|
| KRAS | p.G12D | 27% | I |
| TP53 | p.R248Q | 39% | II |
| SMAD4 | p.R361H | 18% | II |
| ARID1A | p.Q563* | 22% | III |
Interpretation drafted by PierianDx scientistAwaiting laboratory sign-out
What’s next for your clinical reporting program?
Whether you need additional interpretation capacity, want to build internal expertise, or both, let’s talk about the approach that fits your program.
FAQ
Questions about Clinical Operations
What is Interpretation Services?
Interpretation Services provides scientific interpretation capacity for laboratories that need support reviewing and interpreting clinical genomic cases. PierianDx variant scientists perform scoped case interpretation within CGW, while clinical review and sign-out remain with the laboratory .
Do I need an internal variant interpretation team to use Interpretation Services?
No. Interpretation Services can provide additional scientific interpretation capacity whether your laboratory is building internal expertise or already has an established review team. If you want to develop interpretation capability internally, the Variant Analyst Certification Program can also be used alongside Interpretation Services.
Can Interpretation Services and the Variant Analyst Certification Program be used together?
Yes. Interpretation Services can provide additional interpretation capacity while internal analysts build expertise through the Variant Analyst Certification Program. The two offerings can be used independently or together, depending on the laboratory’s needs.
Does interpretation happen within CGW?
Yes. PierianDx variant scientists review and interpret scoped cases within Clinical Genomics Workspace (CGW), and completed interpretations are returned to the customer through the CGW workflow.
What types of interpretation support are currently available?
Interpretation Services supports somatic and germline case interpretation as well as scoped validation-case support. Services can include evidence review, variant classification, reporting support, and additional scientific review for challenging variants or interpretation questions .